Localization of ASV Integrase-DNA Contacts by Site-Directed Crosslinking and their Structural Analysis

BACKGROUND: We applied crosslinking techniques as a first step in preparation of stable avian sarcoma virus (ASV) integrase (IN)-DNA complexes for crystallographic investigations. These results were then compared with the crystal structures of the prototype foamy virus (PFV) intasome and with publis...

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Autors principals: Peletskaya, Elena, Andrake, Mark, Gustchina, Alla, Merkel, George, Alexandratos, Jerry, Zhou, Dongwen, Bojja, Ravi S., Satoh, Tadashi, Potapov, Mikhail, Kogon, Alex, Potapov, Viktor, Wlodawer, Alexander, Skalka, Anna Marie
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228729/
https://ncbi.nlm.nih.gov/pubmed/22145019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027751
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