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Insulin action is blocked by a monoclonal antibody that inhibits the insulin receptor kinase.

Thirty-six monoclonal antibodies to the human insulin receptor were produced. Thirty-four bound the intracellular domain of the receptor beta subunit, the domain containing the tyrosine-specific kinase activity. Of these 34 antibodies, 33 recognized the rat receptor and 1 was shown to precipitate th...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Morgan, D O, Ho, L, Korn, L J, Roth, R A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1986
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322851/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3455769/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.2.328
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