Insulin action is blocked by a monoclonal antibody that inhibits the insulin receptor kinase.
Thirty-six monoclonal antibodies to the human insulin receptor were produced. Thirty-four bound the intracellular domain of the receptor beta subunit, the domain containing the tyrosine-specific kinase activity. Of these 34 antibodies, 33 recognized the rat receptor and 1 was shown to precipitate th...
Gardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
1986
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC322851/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3455769/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.2.328 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|