Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2 mediated regeneration of sinusoidal endothelial cells

The phenotypic attributes and molecular determinants for the regeneration of bone marrow (BM) sinusoidal endothelial cells (SECs) and their contribution to hematopoiesis are unknown. We show that after myelosuppression VEGFR2 activation promotes reassembly of regressed SECs, reconstituting hematopoi...

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書誌詳細
主要な著者: Hooper, Andrea T., Butler, Jason M., Nolan, Daniel J, Kranz, Andrea, Iida, Kaoruko, Kobayashi, Mariko, Kopp, Hans-Georg, Shido, Koji, Petit, Isabelle, Yanger, Kilangsungla, James, Daylon, Witte, Larry, Zhu, Zhenping, Wu, Yan, Pytowski, Bronislaw, Rosenwaks, Zev, Mittal, Vivek, Sato, Thomas N., Rafii, Shahin
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228275/
https://ncbi.nlm.nih.gov/pubmed/19265665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2009.01.006
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