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Concise route to defined stereoisomers of the hydroxy acid of the chondramides
The use of Kobayashi vinylogous aldol reaction in the reaction with acetaldehyde led to anti-aldol product 11. After reductive removal of the chiral auxiliary, the primary alcohol was converted to the allyliodide 14. This compound could be engaged in an Evans alkylation reaction, leading eventually...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3228260/ https://ncbi.nlm.nih.gov/pubmed/22140278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2008.04.109 |
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