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Synthesis of Chondramide A Analogues with Modified β-Tyrosine and Their Biological Evaluation

Starting from cinnamates 9, obtained by Wittig reaction or Heck coupling, the diols 17 were prepared by asymmetric dihydroxylation. This was followed by a regioselective substitution of the 3-OH group with hydrazoic acid under Mitsunobu conditions. Methylation of the 2-OH group and reduction of the...

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Detalhes bibliográficos
Main Authors: Zhdanko, Alexander, Schmauder, Anke, Ma, Christopher I., Sibley, L. David, Sept, D. David, Sasse, Florenz, Maier, Martin E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228261/
https://ncbi.nlm.nih.gov/pubmed/22012705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201101978
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