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Utility of mTOR Inhibition in Hematologic Malignancies
The mammalian target of rapamycin (mTOR) is an intracellular serine/threonine kinase that exists as a downstream component of numerous signaling pathways. The activation of mTOR results in the production of proteins involved in cell metabolism, growth, proliferation, and angiogenesis. Aberrant activ...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
AlphaMed Press
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3228224/ https://ncbi.nlm.nih.gov/pubmed/21632450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2010-0318 |
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