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mTOR inhibition as a Therapeutic Strategy in the Management of Urologic Malignancies
The mammalian target of rapamycin (mTOR) is a protein kinase that regulates protein translation, cell growth and apoptosis. Recently, there has been an enormous increase in our understanding on molecular mechanisms underlying the therapeutics of rapamycin in cancer. Alterations in the pathway regula...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587303/ https://ncbi.nlm.nih.gov/pubmed/18566209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-2408 |
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