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FLT3 Inhibition as Therapy in Acute Myeloid Leukemia: A Record of Trials and Tribulations

Acute myeloid leukemia (AML) is a hematologic malignancy with a poor prognosis. Approximately one quarter of the patients with AML also carry an internal tandem duplication (ITD) mutation in the gene encoding FMS-like tyrosine kinase 3 (FLT3), which has a significantly deleterious impact on prognosi...

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Sonraí Bibleagrafaíochta
Main Authors: Fathi, Amir T., Chabner, Bruce A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: AlphaMed Press 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228152/
https://ncbi.nlm.nih.gov/pubmed/21765192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2011-0084
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