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FLT3 Inhibition as Therapy in Acute Myeloid Leukemia: A Record of Trials and Tribulations
Acute myeloid leukemia (AML) is a hematologic malignancy with a poor prognosis. Approximately one quarter of the patients with AML also carry an internal tandem duplication (ITD) mutation in the gene encoding FMS-like tyrosine kinase 3 (FLT3), which has a significantly deleterious impact on prognosi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
AlphaMed Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3228152/ https://ncbi.nlm.nih.gov/pubmed/21765192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2011-0084 |
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