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Maintenance therapy for FLT3-ITD-mutated acute myeloid leukemia

FLT3-ITD is a constitutively activated variant of the FLT3 tyrosine kinase receptor. Its expression in acute myeloid leukemia (AML) is associated with a poor prognosis. Due to this, the development of tyrosine kinase inhibitors (TKI) blocking FLT3-ITD became a rational therapeutic concept. This revi...

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Bibliografske podrobnosti
izdano v:Haematologica
Glavni avtor: Burchert, Andreas
Format: Artigo
Jezik:Inglês
Izdano: Fondazione Ferrata Storti 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927878/
https://ncbi.nlm.nih.gov/pubmed/33472354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.240747
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