Part 3: Pharmacogenetic Variability in Phase II Anticancer Drug Metabolism

Equivalent drug doses may lead to wide interpatient variability in drug response to anticancer therapy. Known determinants that may affect the pharmacological response to a drug are, among others, nongenetic factors, including age, gender, use of comedication, and liver and renal function. Nonethele...

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Библиографические подробности
Главные авторы: Deenen, Maarten J., Cats, Annemieke, Beijnen, Jos H., Schellens, Jan H.M.
Формат: Artigo
Язык:Inglês
Опубликовано: AlphaMed Press 2011
Предметы:
Clinical Pharmacology: Pharmacogenetics: Opportunities for Patient-Tailored Anticancer Therapy
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228134/
https://ncbi.nlm.nih.gov/pubmed/21659608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2010-0260
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