Part 1: Background, Methodology, and Clinical Adoption of Pharmacogenetics

Equivalent drug doses may lead to wide interpatient variability with regard to drug response, reflected by differences in drug activity and normal tissue toxicity. A major factor responsible for this variability is variation among patients in their genetic constitution. Genetic polymorphism may affe...

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Podrobná bibliografie
Hlavní autoři: Deenen, Maarten J., Cats, Annemieke, Beijnen, Jos H., Schellens, Jan H.M.
Médium: Artigo
Jazyk:Inglês
Vydáno: AlphaMed Press 2011
Témata:
Clinical Pharmacology: Pharmacogenetics: Opportunities for Patient-Tailored Anticancer Therapy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228225/
https://ncbi.nlm.nih.gov/pubmed/21632456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2010-0258
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