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Part 3: Pharmacogenetic Variability in Phase II Anticancer Drug Metabolism

Equivalent drug doses may lead to wide interpatient variability in drug response to anticancer therapy. Known determinants that may affect the pharmacological response to a drug are, among others, nongenetic factors, including age, gender, use of comedication, and liver and renal function. Nonethele...

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Detalles Bibliográficos
Autores principales: Deenen, Maarten J., Cats, Annemieke, Beijnen, Jos H., Schellens, Jan H.M.
Formato: Artigo
Lenguaje:Inglês
Publicado: AlphaMed Press 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228134/
https://ncbi.nlm.nih.gov/pubmed/21659608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2010-0260
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