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Identification of Tyrosine Residues in Constitutively Activated Fibroblast Growth Factor Receptor 3 Involved in Mitogenesis, Stat Activation, and Phosphatidylinositol 3-Kinase Activation

Fibroblast growth factor receptor 3 (FGFR3) mutations are frequently involved in human developmental disorders and cancer. Activation of FGFR3, through mutation or ligand stimulation, results in autophosphorylation of multiple tyrosine residues within the intracellular domain. To assess the importan...

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Detalhes bibliográficos
Main Authors: Hart, Kristen C., Robertson, Scott C., Donoghue, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC32277/
https://ncbi.nlm.nih.gov/pubmed/11294897
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