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Identification of Tyrosine Residues in Constitutively Activated Fibroblast Growth Factor Receptor 3 Involved in Mitogenesis, Stat Activation, and Phosphatidylinositol 3-Kinase Activation

Fibroblast growth factor receptor 3 (FGFR3) mutations are frequently involved in human developmental disorders and cancer. Activation of FGFR3, through mutation or ligand stimulation, results in autophosphorylation of multiple tyrosine residues within the intracellular domain. To assess the importan...

詳細記述

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書誌詳細
主要な著者: Hart, Kristen C., Robertson, Scott C., Donoghue, Daniel J.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC32277/
https://ncbi.nlm.nih.gov/pubmed/11294897
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