Upregulation of KCC2 Activity by Zinc-Mediated Neurotransmission via the mZnR/GPR39 Receptor

Vesicular Zn(2+) regulates postsynaptic neuronal excitability upon its corelease with glutamate. We previously demonstrated that synaptic Zn(2+) acts via a distinct metabotropic zinc-sensing receptor (mZnR) in neurons to trigger Ca(2+) responses in the hippocampus. Here, we show that physiological a...

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Main Authors: Chorin, Ehud, Vinograd, Ofir, Fleidervish, Ilya, Gilad, David, Herrmann, Sharon, Sekler, Israel, Aizenman, Elias, Hershfinkel, Michal
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2011
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227684/
https://ncbi.nlm.nih.gov/pubmed/21900570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2205-11.2011
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