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SNARE-dependent upregulation of KCC2 activity following metabotropic zinc receptor (mZnR/GPR39) activation in rat cortical neurons in vitro

The major outward chloride transporter in neurons is the potassium chloride co-transporter 2 (KCC2), critical for maintaining an inhibitory reversal potential for GABA(A) receptor channels. In a recent study, we showed that Zn(2+) regulates GABA(A) reversal potentials in the hippocampus by enhancing...

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書誌詳細
主要な著者: Saadi, Robert A., He, Kai, Hartnett, Karen A., Kandler, Karl, Hershfinkel, Michal, Aizenman, Elias
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358579/
https://ncbi.nlm.nih.gov/pubmed/22441041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2012.03.001
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