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The Zn(2+)-sensing receptor, ZnR/GPR39, upregulates colonocytic Cl(−) absorption, via basolateral KCC1, and reduces fluid loss()

Administration of zinc, as a complement to oral rehydration solutions, effectively diminishes duration and severity of diarrhea, but it is not known whether it merely fulfills a nutritional deficiency, or if zinc has a direct role of regulating solute absorption. We show that Zn(2+) acts via a speci...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Sunuwar, Laxmi, Asraf, Hila, Donowitz, Mark, Sekler, Israel, Hershfinkel, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557417/
https://ncbi.nlm.nih.gov/pubmed/28093242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.01.009
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