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Enhanced ZnR/GPR39 Activity in Breast Cancer, an Alternative Trigger of Signaling Leading to Cell Growth

Acquired resistance to the estrogen receptor (ER) antagonist tamoxifen, is a major obstacle in treatment of breast cancer. Changes in Zn(2+) accumulation and distribution are associated with tamoxifen-resistance and breast cancer progression. The Zn(2+)-sensing G-protein coupled receptor, ZnR/GPR39,...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Ventura-Bixenshpaner, Hila, Asraf, Hila, Chakraborty, Moumita, Elkabets, Moshe, Sekler, Israel, Taylor, Kathryn M., Hershfinkel, Michal
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970167/
https://ncbi.nlm.nih.gov/pubmed/29802348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26459-5
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