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Measuring Tumor Aggressiveness and Targeting Metastatic Lesions with Fluorescent pHLIP
PURPOSE: Malignant cancer foci develop acidic extracellular environments. Mild acidic conditions trigger insertion and folding of the pH (low) insertion peptide (pHLIP(™)) across a cellular membrane, enabling targeting of such lesions. PROCEDURES: We employed optical imaging to follow targeting by f...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3227673/ https://ncbi.nlm.nih.gov/pubmed/21181501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-010-0457-z |
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