Atherosclerotic Plaque Stability Is Affected by the Chemokine CXCL10 in Both Mice and Humans

Background. The chemokine CXCL10 is specifically upregulated during experimental development of plaque with an unstable phenotype. In this study we evaluated the functional consequences of these findings in mice and humans. Methods and Results. In ApoE(−/−) mice, we induced unstable plaque with usin...

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Detalhes bibliográficos
Main Authors: Segers, Dolf, Lipton, Jonathan A., Leenen, Pieter J. M., Cheng, Caroline, Tempel, Dennie, Pasterkamp, Gerard, Moll, Frans L., de Crom, Rini, Krams, Rob
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227498/
https://ncbi.nlm.nih.gov/pubmed/22164344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/936109
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