Atherosclerotic Plaque Stability Is Affected by the Chemokine CXCL10 in Both Mice and Humans

Background. The chemokine CXCL10 is specifically upregulated during experimental development of plaque with an unstable phenotype. In this study we evaluated the functional consequences of these findings in mice and humans. Methods and Results. In ApoE(−/−) mice, we induced unstable plaque with usin...

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Hlavní autoři: Segers, Dolf, Lipton, Jonathan A., Leenen, Pieter J. M., Cheng, Caroline, Tempel, Dennie, Pasterkamp, Gerard, Moll, Frans L., de Crom, Rini, Krams, Rob
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE-Hindawi Access to Research 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227498/
https://ncbi.nlm.nih.gov/pubmed/22164344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/936109
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