Atherosclerotic Plaque Stability Is Affected by the Chemokine CXCL10 in Both Mice and Humans

Background. The chemokine CXCL10 is specifically upregulated during experimental development of plaque with an unstable phenotype. In this study we evaluated the functional consequences of these findings in mice and humans. Methods and Results. In ApoE(−/−) mice, we induced unstable plaque with usin...

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Détails bibliographiques
Auteurs principaux: Segers, Dolf, Lipton, Jonathan A., Leenen, Pieter J. M., Cheng, Caroline, Tempel, Dennie, Pasterkamp, Gerard, Moll, Frans L., de Crom, Rini, Krams, Rob
Format: Artigo
Langue:Inglês
Publié: SAGE-Hindawi Access to Research 2011
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227498/
https://ncbi.nlm.nih.gov/pubmed/22164344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/936109
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