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HIC-5: A Mobile Molecular Scaffold Regulating the Anchorage Dependence of Cell Growth
HIC-5 is a multidomain LIM protein homologous to paxillin that serves as a molecular scaffold at focal adhesions and in the nucleus. It forms mobile molecular units with LIM-only proteins, PINCH, and CRP2 and translocates in and out of the nucleus via a nuclear export signal (NES). Of note, NES of H...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Hindawi Publishing Corporation
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3227459/ https://ncbi.nlm.nih.gov/pubmed/22145007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/426138 |
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