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HIC-5: A Mobile Molecular Scaffold Regulating the Anchorage Dependence of Cell Growth

HIC-5 is a multidomain LIM protein homologous to paxillin that serves as a molecular scaffold at focal adhesions and in the nucleus. It forms mobile molecular units with LIM-only proteins, PINCH, and CRP2 and translocates in and out of the nucleus via a nuclear export signal (NES). Of note, NES of H...

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Detalhes bibliográficos
Main Authors: Shibanuma, Motoko, Mori, Kazunori, Nose, Kiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227459/
https://ncbi.nlm.nih.gov/pubmed/22145007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/426138
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