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A HIC-5- and KLF4-dependent Mechanism Transactivates p21(Cip1) in Response to Anchorage Loss

Anchorage loss elicits a set of responses in cells, such as transcriptional changes, in order to prevent inappropriate cell growth in ectopic environments. However, the mechanisms underlying these responses are poorly understood. In this study, we investigated the transcriptional up-regulation of cy...

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Bibliographic Details
Main Authors: Mori, Kazunori, Hamanaka, Hiroyuki, Oshima, Yukiko, Araki, Yuri, Ishikawa, Fumihiro, Nose, Kiyoshi, Shibanuma, Motoko
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493927/
https://ncbi.nlm.nih.gov/pubmed/23007394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.377721
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