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A Pilot Study of MUC-1/CEA/TRICOM Poxviral-Based Vaccine in Patients with Metastatic Breast and Ovarian Cancer

PURPOSE: PANVAC is a recombinant poxviral vaccine that contains transgenes for MUC-1, CEA and 3 T-cell costimulatory molecules. This study was conducted to obtain preliminary evidence of clinical response in metastatic breast and ovarian cancer patients. EXPERIMENTAL DESIGN: Twenty-six patients were...

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Bibliographische Detailangaben
Hauptverfasser: Mohebtash, Mahsa, Tsang, Kwong-Yok, Madan, Ravi A., Huen, Ngar-Yee, Poole, Diane J., Jochems, Caroline, Jones, Jacquin, Ferrara, Theresa, Heery, Christopher R., Arlen, Philip M., Steinberg, Seth M., Pazdur, Mary, Rauckhorst, Myrna, Jones, Elizabeth C., Dahut, William L., Schlom, Jeffrey, Gulley, James L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227395/
https://ncbi.nlm.nih.gov/pubmed/22068656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0649
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