A Pilot Study of MUC-1/CEA/TRICOM Poxviral-Based Vaccine in Patients with Metastatic Breast and Ovarian Cancer

PURPOSE: PANVAC is a recombinant poxviral vaccine that contains transgenes for MUC-1, CEA and 3 T-cell costimulatory molecules. This study was conducted to obtain preliminary evidence of clinical response in metastatic breast and ovarian cancer patients. EXPERIMENTAL DESIGN: Twenty-six patients were...

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主要な著者: Mohebtash, Mahsa, Tsang, Kwong-Yok, Madan, Ravi A., Huen, Ngar-Yee, Poole, Diane J., Jochems, Caroline, Jones, Jacquin, Ferrara, Theresa, Heery, Christopher R., Arlen, Philip M., Steinberg, Seth M., Pazdur, Mary, Rauckhorst, Myrna, Jones, Elizabeth C., Dahut, William L., Schlom, Jeffrey, Gulley, James L.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227395/
https://ncbi.nlm.nih.gov/pubmed/22068656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0649
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