Phase I Study of a Poxviral TRICOM-Based Vaccine Directed Against the Transcription Factor Brachyury

PURPOSE: The transcription factor brachyury has been shown in preclinical studies to be a driver of the epithelial-to-mesenchymal transition (EMT) and resistance to therapy of human tumor cells. This study describes the characterization of a Modified Vaccinia Ankara (MVA) vector-based vaccine expres...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Cancer Res
Egile Nagusiak: Heery, Christopher R., Palena, Claudia, McMahon, Sheri, Donahue, Renee N., Lepone, Lauren M., Grenga, Italia, Dirmeier, Ulrike, Cordes, Lisa, Marté, Jenn, Dahut, William, Singh, Harpreet, Madan, Ravi A., Fernando, Romaine I., Hamilton, Duane H., Schlom, Jeffrey, Gulley, James L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690815/
https://ncbi.nlm.nih.gov/pubmed/28855356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1087
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