Phase I Study of a Poxviral TRICOM-Based Vaccine Directed Against the Transcription Factor Brachyury

PURPOSE: The transcription factor brachyury has been shown in preclinical studies to be a driver of the epithelial-to-mesenchymal transition (EMT) and resistance to therapy of human tumor cells. This study describes the characterization of a Modified Vaccinia Ankara (MVA) vector-based vaccine expres...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Heery, Christopher R., Palena, Claudia, McMahon, Sheri, Donahue, Renee N., Lepone, Lauren M., Grenga, Italia, Dirmeier, Ulrike, Cordes, Lisa, Marté, Jenn, Dahut, William, Singh, Harpreet, Madan, Ravi A., Fernando, Romaine I., Hamilton, Duane H., Schlom, Jeffrey, Gulley, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690815/
https://ncbi.nlm.nih.gov/pubmed/28855356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1087
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