Phase I Study of a Poxviral TRICOM-Based Vaccine Directed Against the Transcription Factor Brachyury

PURPOSE: The transcription factor brachyury has been shown in preclinical studies to be a driver of the epithelial-to-mesenchymal transition (EMT) and resistance to therapy of human tumor cells. This study describes the characterization of a Modified Vaccinia Ankara (MVA) vector-based vaccine expres...

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Bibliografiske detaljer
Udgivet i:Clin Cancer Res
Main Authors: Heery, Christopher R., Palena, Claudia, McMahon, Sheri, Donahue, Renee N., Lepone, Lauren M., Grenga, Italia, Dirmeier, Ulrike, Cordes, Lisa, Marté, Jenn, Dahut, William, Singh, Harpreet, Madan, Ravi A., Fernando, Romaine I., Hamilton, Duane H., Schlom, Jeffrey, Gulley, James L.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5690815/
https://ncbi.nlm.nih.gov/pubmed/28855356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1087
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