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Fluorinated Amino-Derivatives of the Sesquiterpene Lactone, Parthenolide, as (19)F NMR Probes in Deuterium-Free Environments
The design, synthesis, and biological activity of fluorinated amino-derivatives of the sesquiterpene lactone, parthenolide, are described. A fluorinated aminoparthenolide analogue with biological activity similar to the parent natural product was discovered, and its X-ray structure was obtained. Thi...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3227115/ https://ncbi.nlm.nih.gov/pubmed/22029741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201114t |
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