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Covalent Modification of Human Serum Albumin by the Natural Sesquiterpene Lactone Parthenolide

The reactivity of parthenolide (PRT), a natural sesquiterpene lactone from Tanacetum parthenium (Asteraceae), with human serum albumin (HSA) was studied by UHPLC/+ESI-QqTOF MS analysis after tryptic digestion of albumin samples after incubation with this compound. It was found that the single free c...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Plöger, Michael, Sendker, Jandirk, Langer, Klaus, Schmidt, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272280/
https://ncbi.nlm.nih.gov/pubmed/25859779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20046211
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