The Natural Sesquiterpene Lactones Arglabin, Grosheimin, Agracin, Parthenolide, and Estafiatin Inhibit T Cell Receptor (TCR) Activation

Inhibition of the T cell receptor (TCR) pathway represents an effective strategy for the treatment of T cell-mediated inflammatory and autoimmune diseases. To identify natural compounds that could inhibit inflammatory T cell responses, we screened 13 sesquiterpene lactones, including achillin, argla...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Phytochemistry
Prif Awduron: Schepetkin, Igor A., Kirpotina, Liliya N., Mitchell, Pete T., Kishkentaeva, Anarkul S., Shaimerdenova, Zhanar R., Atazhanova, Gayane A., Adekenov, Sergazy M., Quinn, Mark T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5750123/
https://ncbi.nlm.nih.gov/pubmed/29216473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phytochem.2017.11.010
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