The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells

Recent studies have described malignant stem cells as central to the initiation, growth, and potential relapse of acute and chronic myelogenous leukemia (AML and CML). Because of their important role in pathogenesis, rare and biologically distinct leukemia stem cells (LSCs) represent a critical targ...

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Detalhes bibliográficos
Main Authors: Guzman, Monica L., Rossi, Randall M., Karnischky, Lilliana, Li, Xiaojie, Peterson, Derick R., Howard, Dianna S., Jordan, Craig T.
Formato: Artigo
Idioma:Inglês
Publicado em: © 2005 by The American Society of Hematology 2005
Assuntos:
Plenary Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895029/
https://ncbi.nlm.nih.gov/pubmed/15687234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-10-4135
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