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Fluorinated Amino-Derivatives of the Sesquiterpene Lactone, Parthenolide, as (19)F NMR Probes in Deuterium-Free Environments

The design, synthesis, and biological activity of fluorinated amino-derivatives of the sesquiterpene lactone, parthenolide, are described. A fluorinated aminoparthenolide analogue with biological activity similar to the parent natural product was discovered, and its X-ray structure was obtained. Thi...

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Autors principals: Woods, James R., Mo, Huaping, Bieberich, Andrew A., Alavanja, Tanja, Colby, David A.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227115/
https://ncbi.nlm.nih.gov/pubmed/22029741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201114t
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