Metabotropic Glutamate Receptor 5 Antagonism with Fenobam: Examination of Analgesic Tolerance and Side Effect Profile in Mice

BACKGROUND: The metabotropic glutamate receptor 5 noncompetitive antagonist fenobam is analgesic in rodents. Future development of fenobam as an analgesic in humans will require a favorable long-term treatment profile and a lack of significant deleterious side effects. This study aimed to determine...

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Bibliografiset tiedot
Päätekijät: Montana, Michael C., Conrardy, Beth A., Cavallone, Laura F., Kolber, Benedict J., Rao, Leslie K., Greco, Suellen C., Gereau, Robert W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226928/
https://ncbi.nlm.nih.gov/pubmed/22037639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318238c051
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