Carregant...

Discovery, Synthesis, SAR Development of a Series of N-4-(2,5-dioxopyrrolidin-1-yl)-phenylpicolinamides (VU0400195, ML182): Characterization of a Novel Positive Allosteric Modulator of the Metabotropic Glutamate Receptor 4 (mGlu(4)) with Oral Efficacy in an anti-Parkinsonian Animal Model

There is an increasing amount of literature data showing the positive effects on preclinical anti-Parkinsonian rodent models with selective positive allosteric modulators of metabotropic glutamate receptor 4 (mGlu(4)). However, most of the data generated utilize compounds that have not been optimize...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Jones, Carrie K., Engers, Darren W., Thompson, Analisa D., Field, Julie R., Blobaum, Anna L., Lindsley, Stacey R., Zhou, Ya, Gogliotti, Rocco D., Jadhav, Satyawan, Zamorano, Rocio, Bogenpohl, Jim, Smith, Yoland, Morrison, Ryan, Daniels, J. Scott, Weaver, C. David, Conn, P. Jeffrey, Lindsley, Craig W., Niswender, Colleen M., Hopkins, Corey R.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226828/
https://ncbi.nlm.nih.gov/pubmed/21966889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200956q
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!