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Use of PROTACS as molecular probes of angiogenesis
Small molecules designed to specifically activate or inactivate protein functions have been useful to study biological processes. PROTACS are small molecule chimera which comprise a ligand and a peptide recognition motif for an E3 ligase. These novel reagents exploit the ubiquitin-mediated proteasom...
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| Main Authors: | , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2005
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3226786/ https://ncbi.nlm.nih.gov/pubmed/15876533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2005.04.008 |
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