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Impact of linker length on the activity of PROTACs

Conventional genetic approaches have provided a powerful tool in the study of proteins. However, these techniques often preclude selective manipulation of temporal and spatial protein functions, which is crucial for the investigation of dynamic cellular processes. To overcome these limitations, a sm...

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Detalhes bibliográficos
Main Authors: Cyrus, Kedra, Wehenkel, Marie, Choi, Eun-Young, Han, Hyeong-Jun, Lee, Hyosung, Swanson, Hollie, Kim, Kyung-Bo
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835402/
https://ncbi.nlm.nih.gov/pubmed/20922213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0mb00074d
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