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Impact of linker length on the activity of PROTACs

Conventional genetic approaches have provided a powerful tool in the study of proteins. However, these techniques often preclude selective manipulation of temporal and spatial protein functions, which is crucial for the investigation of dynamic cellular processes. To overcome these limitations, a sm...

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Библиографические подробности
Главные авторы: Cyrus, Kedra, Wehenkel, Marie, Choi, Eun-Young, Han, Hyeong-Jun, Lee, Hyosung, Swanson, Hollie, Kim, Kyung-Bo
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835402/
https://ncbi.nlm.nih.gov/pubmed/20922213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0mb00074d
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