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Compartmental Modeling of (11)C-HOMADAM Binding to the Serotonin Transporter in the Healthy Human Brain
The novel PET radioligand (11)C-N,N-dimethyl-2-(2′-amino-4′-hydroxymethylphenylthio)benzylamine ((11)C-HOMADAM) binds with high affinity and selectively to the serotonin transporter (SERT). The purpose of this study was to develop a reliable kinetic model to describe the uptake of (11)C-HOMADAM in t...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3226704/ https://ncbi.nlm.nih.gov/pubmed/19038997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.108.054262 |
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