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Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1
In human cells, the mRNA export factor NXF1 resides in the nucleoplasm and at nuclear pore complexes. Karyopherin β2 or transportin recognizes a proline–tyrosine nuclear localization signal (PY-NLS) in the N-terminal tail of NXF1 and imports it into the nucleus. Here biochemical and cellular studies...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The American Society for Cell Biology
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3226482/ https://ncbi.nlm.nih.gov/pubmed/21965294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-03-0222 |
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