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Influenza virus targets the mRNA export machinery and the nuclear pore complex

The NS1 protein of influenza A virus is a major virulence factor that is essential for pathogenesis. NS1 functions to impair innate and adaptive immunity by inhibiting host signal transduction and gene expression, but its mechanisms of action remain to be fully elucidated. We show here that NS1 form...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Satterly, Neal, Tsai, Pei-Ling, van Deursen, Jan, Nussenzveig, Daniel R., Wang, Yaming, Faria, Paula A., Levay, Agata, Levy, David E., Fontoura, Beatriz M. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794296/
https://ncbi.nlm.nih.gov/pubmed/17267598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610977104
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