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Influenza virus targets the mRNA export machinery and the nuclear pore complex

The NS1 protein of influenza A virus is a major virulence factor that is essential for pathogenesis. NS1 functions to impair innate and adaptive immunity by inhibiting host signal transduction and gene expression, but its mechanisms of action remain to be fully elucidated. We show here that NS1 form...

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Hlavní autoři: Satterly, Neal, Tsai, Pei-Ling, van Deursen, Jan, Nussenzveig, Daniel R., Wang, Yaming, Faria, Paula A., Levay, Agata, Levy, David E., Fontoura, Beatriz M. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794296/
https://ncbi.nlm.nih.gov/pubmed/17267598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610977104
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