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Influenza virus targets the mRNA export machinery and the nuclear pore complex

The NS1 protein of influenza A virus is a major virulence factor that is essential for pathogenesis. NS1 functions to impair innate and adaptive immunity by inhibiting host signal transduction and gene expression, but its mechanisms of action remain to be fully elucidated. We show here that NS1 form...

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Bibliografiske detaljer
Main Authors: Satterly, Neal, Tsai, Pei-Ling, van Deursen, Jan, Nussenzveig, Daniel R., Wang, Yaming, Faria, Paula A., Levay, Agata, Levy, David E., Fontoura, Beatriz M. A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794296/
https://ncbi.nlm.nih.gov/pubmed/17267598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610977104
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