β-Catenin and Smad3 regulate the activity and stability of myocardin-related transcription factor during epithelial–myofibroblast transition

Injury to the adherens junctions (AJs) synergizes with transforming growth factor-β1 (TGFβ) to activate a myogenic program (α-smooth muscle actin [SMA] expression) in the epithelium during epithelial–myofibroblast transition (EMyT). Although this synergy plays a key role in organ fibrosis, the under...

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Bibliographic Details
Main Authors: Charbonney, Emmanuel, Speight, Pam, Masszi, András, Nakano, Hiroyasu, Kapus, András
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2011
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226468/
https://ncbi.nlm.nih.gov/pubmed/21965288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-04-0335
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