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T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice
Many autoimmune diseases exhibit familial aggregation, indicating that they have genetic determinants. Single nucleotide polymorphisms in PTPN2, which encodes T cell protein tyrosine phosphatase (TCPTP), have been linked with the development of several autoimmune diseases, including type 1 diabetes...
Gorde:
Egile Nagusiak: | , , , , , , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
American Society for Clinical Investigation
2011
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3226006/ https://ncbi.nlm.nih.gov/pubmed/22080863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59492 |
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