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Protein Solubility and Protein Homeostasis: A Generic View of Protein Misfolding Disorders

According to the “generic view” of protein aggregation, the ability to self-assemble into stable and highly organized structures such as amyloid fibrils is not an unusual feature exhibited by a small group of peptides and proteins with special sequence or structural properties, but rather a property...

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Autors principals: Vendruscolo, Michele, Knowles, Tuomas P.J., Dobson, Christopher M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225949/
https://ncbi.nlm.nih.gov/pubmed/21825020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a010454
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